Save
Adenosine is a chemical found in human cells. There are three different forms: adenosine, adenosine monophosphate (AMP), and adenosine triphosphate (ATP).
Adenosine blocks electrical signals in the heart that cause irregular heart rhythms. ATP might also prevent changes in energy metabolism that cause weight loss in people with advanced cancer.
An injectable form of adenosine is a US FDA-approved prescription drug for a condition involving rapid heart rate (paroxysmal supraventricular tachycardia). It is also used as a prescription drug to help measure blockages in the arteries of the heart. People also use adenosine, AMP, and ATP as supplements for athletic performance, cold sores, and many other purposes, but there is no good evidence to support these uses.
- Cardiovascular disease diagnosis. Adenosine intravenous infusion is FDA-approved for use in cardiac stress testing to diagnose coronary artery disease (CAD).
Login for details - Paroxysmal supraventricular tachycardia. Adenosine intravenous injection is FDA-approved for acute management of paroxysmal supraventricular tachycardia (PSVT).
Login for details
- Cachexia. Intravenous adenosine triphosphate may be beneficial in cachexic patients with various cancers. Oral adenosine has not been evaluated for this purpose.
Login for details
- Myocardial Infarction (MI). Intravenous or intracoronary adenosine does not seem to be beneficial for acute coronary syndrome. Oral adenosine has not been evaluated for this purpose.
Login for details - Postoperative nausea and vomiting (PONV). Parenteral adenosine does not seem to be beneficial for PONV. Oral adenosine has not been evaluated for this purpose.
Login for details - Postoperative pain. Parenteral adenosine does not seem to be helpful for postoperative pain. Oral adenosine has not been evaluated for this purpose.
Login for details
- Androgenic alopecia. It is unclear if topical adenosine is beneficial in patients with androgenic alopecia.
Login for details - Athletic performance. It is unclear if oral adenosine triphosphate is beneficial for improving athletic performance.
Login for details - Erectile dysfunction (ED). Oral adenosine monophosphate has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Login for details - Hearing loss. Oral adenosine triphosphate has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Login for details - Herpes labialis (cold sores). It is unclear if intramuscular adenosine monophosphate is beneficial in patients with herpes labialis. Oral adenosine has not been evaluated for this purpose.
Login for details - Herpes zoster (shingles). It is unclear if intramuscular adenosine monophosphate is beneficial in adults with herpes zoster. Oral adenosine has not been evaluated for this purpose.
Login for details - Lung cancer. Intravenous adenosine triphosphate does not seem to be beneficial in patients with advanced non-small-cell lung cancer (NSCLC). Oral adenosine has not been evaluated for this purpose.
Login for details - Neuropathic pain. It is unclear if intrathecal adenosine is beneficial for experimentally-induced neuropathic pain. Oral adenosine has not been evaluated for this purpose.
Login for details - Porphyria cutanea tarda. It is unclear if oral adenosine monophosphate is beneficial in patients with porphyria cutanea tarda.
Login for details - Pulmonary hypertension. Adenosine given by central venous infusion might be beneficial in patients who develop pulmonary hypertension during cardiac surgery.
Login for details
When taken by mouth: There isn't enough reliable information to know if adenosine is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if adenosine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Carbamazepine (Tegretol)
Interaction Rating=Moderate Be cautious with this combination.
Adenosine can slow down the heartbeat. Taking carbamazepine with adenosine might cause the heart to beat too slowly.
Dipyridamole (Persantine)
Interaction Rating=Major Do not take this combination.
Dipyridamole can slow down how quickly the body gets rid of adenosine. This increases the risk for serious side effects from adenosine. Do not take adenosine if you are taking dipyridamole.
Methylxanthines
Interaction Rating=Minor Be watchful with this combination.
Methylxanthines might block the effects of adenosine. Adenosine is often used by doctors to do a test on the heart. This test is called a cardiac stress test. Stop taking methylxanthines at least 24 hours before a cardiac stress test.
Caffeine-containing herbs and supplements: Using caffeine can decrease the effects of adenosine. Stop taking caffeine-containing products at least 24 hours before a cardiac stress test. Examples of supplements that contain caffeine include black tea, coffee, green tea, guarana, and yerba mate.
Caffeine can decrease the effects of adenosine. Don't consume caffeine-containing foods or drinks for at least 24 hours before a cardiac stress test.
Adenosine is available as a prescription-only IV medicine approved for certain conditions. When used as a supplement, there isn't enough reliable information to know what an appropriate dose of adenosine might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
Acide 5'-adénylique, Adenine Nucleoside, Adénine Nucléoside, Adenine Riboside, Adénine Riboside, Adenosina, Adénosine, Adenosine Phosphate, Adenosine 5'-Triphosphate Disodium, Adenosine; Adenosine Monophosphate (AMP), Adénosine Monophosphate (AMP); Adenosine-5-monophosphate (A5MP), Adénosine-5-monophosphate (A5MP); Adenosine Diphosphate (ADP), Adénosine Diphosphate (ADP); Adenosine Triphosphate (ATP), Phosphate d'Adénosine.
Information on this website is for informational use only and is not intended to replace professional medical advice, diagnosis, or treatment. While evidence-based, it is not guaranteed to be error-free and is not intended to meet any particular user’s needs or requirements or to cover all possible uses, safety concerns, interactions, outcomes, or adverse effects. Always check with your doctor or other medical professional before making healthcare decisions (including taking any medication) and do not delay or disregard seeking medical advice or treatment based on any information displayed on this website.
© TRC Healthcare 2023. All rights reserved. Use and/or distribution is permitted only pursuant to a valid license or other permission from TRC Healthcare.
Licensed from Therapeutic Research Center, LLC
Copyright © 1995-2023 by Therapeutic Research Center, LLC. All Rights Reserved.