+ Add to myCart

Avocado soy unsaponifiables are chemicals that are found in avocado and soybean oils. These chemicals are mixed together to form avocado soy unsaponifiable products.

Avocado soy unsaponifiables are taken for osteoarthritis. They are also used for back pain, and hot flashes, but there is no good scientific evidence to support these uses.

Don't confuse avocado soy unsaponifiables with compounds made only from avocado, avocado sugar, soybean, or soybean oil.

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Avocado soy unsaponifiables include chemicals like vitamin E, plant fats, and others. The mixture of these chemicals seems to reduce swelling in the joints and other places in the body.

When taken by mouth: Taking avocado soy unsaponifiables is POSSIBLY SAFE for adults when specific products (Piascledine 300 or Flexi-Smart) are taken for up to 3 years. Side effects to avocado soy unsaponifiables are rare but might include stomach problems, diarrhea, constipation, headache, rash, and liver injury.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if avocado soy unsaponifiables are safe to take when pregnant or breast feeding. Stay on the safe side and avoid use.

There are no known interactions with medications. Before taking this product, talk with your health professional if you take any medications.

There are no known interactions with herbs and supplements.

There are no known interactions with foods.


  • For osteoarthritis: A specific product containing avocado soy unsaponifiables (Piascledine 300, Laboratoires Expanscience) 300 mg each day for up to 3 years.

ASU, ASU-NMX 1000TM, ASU Expanscience, Avoca ASU, Avosol, Dasuquin, Piascledine 300.

Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.

For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.

© Copyright 1995-2021. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.

trclogo Licensed from Therapeutic Research Center, LLC Copyright © 1995-2023 by Therapeutic Research Center, LLC. All Rights Reserved.