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Bacillus coagulans is a type of bacteria. It is used similarly to lactobacillus and other probiotics as "beneficial" bacteria.

People take Bacillus coagulans for irritable bowel syndrome (IBS), diarrhea, gas, airway infections, and many other conditions, but there is no good scientific evidence to support these uses.

Bacillus coagulans produces lactic acid and is often misclassified as lactobacillus. In fact, some commercial products containing Bacillus coagulans are marketed as Lactobacillus sporogenes. Unlike lactic acid bacteria such as lactobacillus or bifidobacteria, Bacillus coagulans forms spores. Spores are an important factor in telling Bacillus coagulans apart from other lactic acid bacteria.

There is not enough information to know how Bacillus coagulans might work for medical purposes. Some research shows that Bacillus coagulans might increase immune system function and decrease harmful bacteria.

When taken by mouth: Bacillus coagulans is POSSIBLY SAFE when taken by mouth. Research shows that Bacillus coagulans in doses of 2 billion colony-forming units (CFUs) daily can be safely used for up to 3 months. Lower doses of Bacillus coagulans up to 100 million CFUs daily can be safely used for up to 1 year.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information about the safety of taking Bacillus coagulans if you are pregnant or breast feeding. Stay on the safe side and avoid use.

Children: Bacillus coagulans is POSSIBLY SAFE when taken by mouth in infants and children. Some research has shown that Bacillus coagulans up to 100 million colony-forming units daily can be safely used by infants for up to one year.

Antibiotic drugs

Interaction Rating=Moderate Be cautious with this combination.

Antibiotics are used to reduce harmful bacteria in the body. Antibiotics can also reduce other bacteria in the body. Taking antibiotics along with Bacillus coagulans might reduce the potential benefits of Bacillus coagulans. To avoid this potential interaction take Bacillus coagulans products at least 2 hours before or after antibiotics.

Medications that decrease the immune system (Immunosuppressants)

Interaction Rating=Moderate Be cautious with this combination.

Bacillus coagulans might increase the immune system. Taking Bacillus coagulans along with medications that decrease the immune system might decrease the effectiveness of medications that decrease the immune system.
Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

There are no known interactions with herbs and supplements.

There are no known interactions with foods.

The following doses have been studied in scientific research:

ADULTS

BY MOUTH:

  • For a long-term disorder of the large intestines that causes stomach pain (irritable bowel syndrome or IBS): Bacillus coagulans (Lactospore, Sabinsa Corporation) 2 billion colony-forming units daily for 90 days. Bacillus coagulans (GanedenBC30, Ganeden Biotech Inc.) 300 million to 2 billion colony-forming units daily for 8 weeks. Bacillus coagulans 2 billion colony-forming units three times daily for 80 days. Also, a specific combination product (Colinox, DMG Italia SRL) containing Bacillus coagulans and simethicone has been used after each meal three times daily for 4 weeks.

B. Coagulans, Bacillus Bacteria, Bacillus Probiotics, Bactéries Bacilles, Bactéries à Gram Positif Sporogènes, Bactérie Gram Positive en Forme de Bâtonnet, Gram Positive Spore-Forming Rod, L. Sporogenes, Lactobacillus Sporogenes, Lactobacillus Sporogènes, Probiotic, Probiotique, Spore-Forming Lactobacillus.

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