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Benfotiamine is similar to thiamine (vitamin B1), but is absorbed by the body better than thiamine. The body changes benfotiamine to thiamine.
Since the body absorbs benfotiamine better than thiamine, benfotiamine can increase how much thiamine is in the body. This may help prevent or treat certain symptoms or diseases caused by low thiamine levels. Benfotiamine can be made by certain plants, such as garlic and onion. It can also be made in a lab.
People use benfotiamine for nerve damage caused by diabetes (diabetic neuropathy). It is also used for alcohol use disorder, Alzheimer disease, arthritis, and other conditions, but there is no good scientific evidence to support most of these uses.
- Diabetic neuropathy. Oral benfotiamine might improve symptoms of diabetic neuropathy.
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- Diabetic nephropathy. Oral benfotiamine does not seem to improve markers of diabetic nephropathy.
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- Alcohol use disorder. Small clinical studies suggest that oral benfotiamine may modestly improve symptoms and reduce alcohol consumption in some patients with alcohol use disorder.
Login for details - Alzheimer disease. It is unclear if oral benfotiamine helps to prevent Alzheimer disease onset or progression.
Login for details - Osteoarthritis. Oral benfotiamine has only been evaluated in combination with other B vitamins; its effect when used alone is unclear.
Login for details - Peripheral neuropathy. It is unclear if oral benfotiamine is beneficial in patients with alcohol-induced peripheral neuropathy.
Login for details - Rheumatoid arthritis (RA). Oral benfotiamine has only been evaluated in combination with other B vitamins; its effect when used alone is unclear.
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When taken by mouth: Benfotiamine is likely safe at doses of up to 600 mg daily for up to 24 weeks. Side effects are rare, but some people have reported stomach problems and skin rashes.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if benfotiamine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.It is not known if Benfotiamine interacts with any medicines. Before taking Benfotiamine, talk with your healthcare professional if you take any medications.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
Benfotiamine is most often used by adults in doses of 150-600 mg by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Benfothiamine, Benfotiamin, S-benzoylthiamine O-monophosphate
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