Beta-glucans are soluble fibers that come from the cell walls of bacteria, fungi, yeasts, and some plants. They might lower the risk for heart disease.
Beta-glucans might prevent the body from absorbing cholesterol from food. They might also stimulate the immune system by increasing chemicals that prevent infections. The US FDA allows products containing at least 750 mg of beta-glucans to have a health claim stating that they might reduce heart disease risk.
Beta-glucans are most commonly used for heart disease and high cholesterol. They are also used for many other conditions, such as eczema and diabetes, but there is no good scientific evidence to support most of these other uses.
- Coronary heart disease (CHD).  Consuming products containing at least 3.6 grams of soluble fiber, including beta-glucans, per day may reduce the risk of CHD when consumed as part of a diet low in saturated fat and cholesterol.
Login for details - Hypercholesterolemia.  Oral beta-glucans reduce low-density lipoprotein (LDL) cholesterol levels.
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- Aging. Login for details
- Allergic rhinitis (hay fever).  It is unclear if oral beta-glucans are beneficial for reducing symptoms of allergic rhinitis.
Login for details - Atopic dermatitis (eczema).  It is unclear if topical beta-glucans are beneficial for atopic dermatitis.
Login for details - Benign prostatic hyperplasia (BPH). Login for details
- Cancer. Login for details
- Canker sores.  It is unclear if oral beta-glucans are beneficial for canker sores.
Login for details - Chronic fatigue syndrome (CFS). Login for details
- Critical illness (trauma).  It is unclear if oral beta-glucans are beneficial for patients with critical illness.
Login for details - Diabetes.  Small clinical studies in children and adults with type 1 diabetes suggest that beta-glucans do not improve blood glucose levels. It is unclear if oral beta-glucans are beneficial for patients with type 2 diabetes.
Login for details - Exercise-induced respiratory infections.  There is conflicting evidence about the effects of beta-glucans on respiratory infections in athletes following competitive events.
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- Hepatitis. Login for details
- Hypertension.  It is unclear if oral beta-glucans are beneficial for hypertension; the available evidence is conflicting.
Login for details - Inflammatory bowel disease (IBD).  Oral beta-glucans have only been evaluated in combination with other ingredients; their effect when used alone is unclear.
Login for details - Irritable bowel syndrome (IBS).  Oral beta-glucans have only been evaluated in combination with other ingredients; their effect when used alone is unclear.
Login for details - Laser skin resurfacing.  It is unclear if topical beta-glucans are beneficial for improving recovery from laser skin resurfacing.
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- Metabolic syndrome.  It is unclear if oral beta-glucans are beneficial for metabolic syndrome.
Login for details - Multiple sclerosis (MS). Login for details
- Obesity.  It is unclear if oral beta-glucans are beneficial for obesity.
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- Postoperative pain.  It is unclear if oral beta-glucans are beneficial for reducing abdominal pain after surgery for intestinal polyps.
Login for details - Rheumatoid arthritis (RA). Login for details
- Upper respiratory tract infection (URTI).  It is unclear if oral beta-glucans are beneficial for URTI prevention.
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When taken by mouth: Beta-glucans are commonly consumed in foods. Taking larger amounts of beta-glucans as medicine is possibly safe for up to 8-12 weeks. There have been no reported side effects from taking beta-glucans by mouth.
When applied to the skin: Beta-glucans are possibly safe when used for a short time period. They can cause skin rash in some people.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if beta-glucans are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Medications that decrease the immune system (Immunosuppressants)
Interaction Rating=Moderate Be cautious with this combination.
Beta glucans increase the immune system. By increasing the immune system beta glucans might decrease the effectiveness of medications that decrease the immune system.
Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.
Herbs and supplements that might lower blood pressure: Beta-glucans might lower blood pressure. Taking it with other supplements that have the same effect might cause blood pressure to drop too much.
There are no known interactions with foods.
Beta-glucans that come from oats or barley have most often been used by adults in doses of 2-6 grams by mouth daily for 3-12 weeks. Beta-glucans that come from yeast have most often been used in doses of 250-500 mg by mouth daily for 4-12 weeks. Beta-glucans are also applied to the skin in creams. Speak with a healthcare provider to find out what dose or product might be best for a specific condition.
-3,1-6-beta-glucan, 1-3,1-6-bêta-glucane, B-Glucane d'Avoine, Barley Beta-Glucan, Barley B-Glucan, beta-1,3-D-glucan, Beta-1,3/1,6-D-Glucan, Bêta-1,3/1,6-D-Glucane, Beta 1,3/1,6 Glucan, Beta 1,3/1,6 Glucane, Bêta-1,3 / 1,6 Glucanes, Beta-1,3 / 1,6 Glucans, Beta -1,3-D Glucan, Bêta -1,3-D Glucane, Bêta-1,3-D-glucane, Beta-1,3-Glucan, Bêta-1,3-Glucane, Beta 1,3 Glucan, Bêta 1,3 Glucane, Beta 1,6 Glucan, Bêta 1,6 Glucane, beta-1-6,1,3-beta-glucan, Beta 1,3 Glucans, Bêta 1,3 Glucanes, Beta Glucan, Beta-Glucan, Bêta-Glucane, Bêta-Glucane d'Avoine, Bêta-Glucane d'Orge, Bêta-Glucane Dérivé de la Levure, Bêta-glucanes, Beta Glucanos, Beta Glycans, Beta-Glycans, Oat Beta Glucan, Oat B-Glucan, Pleuran, Yeast-Derived Beta Glucan.
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