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Brussels Sprout Info

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Brussels sprout is a leafy green vegetable that is commonly eaten as a food source or as a medicine.

Brussels sprout is taken by mouth for constipation and to prevent cancer, heart disease, diabetes, stroke, and other conditions. But there is no good scientific evidence to support these uses.

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Brussels sprout contains chemicals that are thought to help prevent cancer. For breast cancer, eating Brussels sprout might change the way estrogen is used in the body, which might reduce the risk of breast cancer. Brussels sprout also has antioxidant activity.

When taken by mouth: Brussels sprout is LIKELY SAFE when consumed in food amounts. But eating Brussels sprout might cause gas.

There isn't enough reliable information to know if Brussels sprout is safe or what the side effects might be when taken by mouth as a medicine.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if Brussels sprout is safe to use in medicinal amounts when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Irritable bowel syndrome (IBS): Eating Brussels sprout might cause gas. This could make symptoms of IBS worse.

Acetaminophen (Tylenol, others)

Interaction Rating=Moderate Be cautious with this combination.

The body breaks down acetaminophen (Tylenol, others) to a get rid of it. Brussels sprout might increase the breakdown of acetaminophen (Tylenol, others). Taking Brussels sprout along with acetaminophen (Tylenol, others) might decrease the effectiveness of acetaminophen (Tylenol, others).

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)

Interaction Rating=Moderate Be cautious with this combination.

Some medications are changed and broken down by the liver.

Brussels sprout might increase how quickly the liver breaks down some medications. Taking Brussels sprout along with some medications that are changed by the liver can decrease the effectiveness of some medications. Before taking Brussels sprout talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.

Medications changed by the liver (Glucuronidated drugs)

Interaction Rating=Moderate Be cautious with this combination.

The liver helps the body break down and change some medications. The body breaks down some medications to get rid of them. Brussels sprout might increase how quickly the body breaks down some medications changed by the liver. Taking Brussels sprout along with these medications changed by the liver might decrease the effectiveness of some medications changed by the liver.

Some of these medications changed by the liver include acetaminophen, atorvastatin (Lipitor), diazepam (Valium), digoxin, entacapone (Comtan), estrogen, irinotecan (Camptosar), lamotrigine (Lamictal), lorazepam (Ativan), lovastatin (Mevacor), meprobamate, morphine, oxazepam (Serax), and others.

Oxazepam (Serax)

Interaction Rating=Moderate Be cautious with this combination.

The body breaks down oxazepam (Serax) to get rid of it. Brussels sprout can increase how quickly the body gets rid of oxazepam (Serax). Taking Brussels sprout along with oxazepam (Serax) might decrease the effectiveness of oxazepam (Serax).

Warfarin (Coumadin)

Interaction Rating=Moderate Be cautious with this combination.

Brussels sprout contains large amounts of vitamin K. Vitamin K is used by the body to help blood clot. Warfarin (Coumadin) is used to slow blood clotting. By helping the blood clot, Brussels sprout might decrease the effectiveness of warfarin (Coumadin). Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.

There are no known interactions with herbs and supplements.

There are no known interactions with foods.

The appropriate dose of Brussels sprout depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Brussels sprout. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

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