+ Add to myCart

Cat's claw is a vine that grows in the rainforest in South and Central America. The two most common species are Uncaria tomentosa and Uncaria guianensis.

Cat's claw root and bark contain chemicals that might stimulate the immune system, kill cancer cells, and fight viruses.

People use cat's claw for cancer, osteoarthritis, rheumatoid arthritis (RA), viral infections, and other conditions, but there is no good scientific evidence to support any of these uses. There is also no good evidence to support using cat's claw for COVID-19.

Don't confuse cat's claw with cat's foot or devil's claw. These are different plants.

No data available.
No data available.
No data available.
No data available.
No data available.
No data available.
No data available.
Info
No data available.

When taken by mouth: Cat's claw is possibly safe for most people when taken for up to 6 months.

When applied to the skin: There isn't enough reliable information to know if cat's claw is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy: Taking cat's claw by mouth is possibly unsafe during pregnancy. Avoid using.

Breast-feeding: There isn't enough reliable information to know if cat's claw is safe to use when breast-feeding. Stay on the safe side and avoid use.

Auto-immune diseases such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), or other similar conditions: Cat's claw might cause the immune system to become more active. This could increase the symptoms of auto-immune diseases. If you have one of these conditions, it's best to avoid using cat's claw without consulting with your healthcare provider.

Parkinson disease: There is a concern that cat's claw might make tremors or movements worse in people with Parkinson disease. Consult with your healthcare provider before using cat's claw.

Surgery: There is a concern that cat's claw might make bleeding control difficult during surgery. Stop taking cat's claw at least 2 weeks before a scheduled surgery.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)

Interaction Rating=Moderate Be cautious with this combination.

Some medications are changed and broken down by the liver.

Cat's claw might decrease how quickly the liver breaks down some medications. Taking cat's claw along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking cat's claw, talk to your healthcare provider if you are taking any medications that are changed by the liver.

Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others.

Medications for high blood pressure (Antihypertensive drugs)

Interaction Rating=Moderate Be cautious with this combination.

Cat's claw seems to decrease blood pressure. Taking cat's claw along with medications for high blood pressure might cause your blood pressure to go too low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Medications that decrease the immune system (Immunosuppressants)

Interaction Rating=Moderate Be cautious with this combination.

Cat's claw might increase the immune system. By increasing the immune system cat's claw might decrease the effectiveness of medications that decrease the immune system.

Some medications that decrease the immune system include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

Herbs and supplements that might lower blood pressure: Cat's claw might lower blood pressure. Taking it with other supplements that have the same effect might cause blood pressure to drop too much. Examples of supplements with this effect include andrographis, casein peptides, L-arginine, niacin, and stinging nettle.
Herbs and supplements that might slow blood clotting: Cat's claw might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.

There are no known interactions with foods.

Cat's claw has most often been used by adults in doses of 60-300 mg by mouth daily for 8-24 weeks. Cat's claw extract is also used in gels and sprays. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition.

Griffe du Chat, Hawk's Claw, Liane du Pérou, Life-giving Vine of Peru, Peruvian Liana, Samento, Uña de Gato, Uncaria guianensis, Uncaria tomentosa.

Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.

For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.

© Copyright 1995-2021. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.

trclogo Licensed from Therapeutic Research Center, LLC Copyright © 1995-2023 by Therapeutic Research Center, LLC. All Rights Reserved.