Collagen peptides are very small pieces of protein from animal collagen. Collagen is one of the materials that makes up cartilage, bone, and skin.
Collagen peptides are made by breaking down whole collagen proteins into smaller pieces. When taken by mouth, collagen peptides seem to build up in the skin and cartilage. This might help improve some skin and joint conditions.
Collagen peptides are used for aging skin and osteoarthritis. They are also used for osteoporosis, brittle nails, muscle strength, and many other purposes, but there is no good scientific evidence to support most of these uses.
Don't confuse collagen peptides with collagen type I (native), collagen type II (native), or gelatin.
- Aging skin.  Oral collagen peptides seem to improve skin hydration and elasticity in older adults. However, it is unclear if any improvements related to wrinkles are cosmetically important.
Login for details
- Muscle strength.  Most research suggests that oral collagen peptides do not improve leg strength. However, they may improve hand-grip strength and fat-free mass.
Login for details
- Acne. Login for details
- Androgenic alopecia.  Oral collagen peptides have only been evaluated in combination with other ingredients, their effect when used alone is unclear.
Login for details - Athletic performance.  It is unclear if oral collagen peptides improve performance in most athletes.
Login for details - Atopic dermatitis (eczema).  It is unclear if oral or topical collagen peptides are beneficial for improving the severity of eczema.
Login for details - Burns.  Some preliminary clinical research suggests that oral collagen peptides might reduce the time needed for burn healing.
Login for details - Brittle nails.  One small clinical study suggests that oral collagen peptides may improve nail health in people with brittle nails.
Login for details - Cellulite.  One small clinical study suggests that oral collagen peptides may reduce cellulite.
Login for details - Cognitive function.  It is unclear if oral collagen peptides are beneficial for improving memory.
Login for details - Dermatoporosis.  One small clinical study suggests that using oral or topical collagen peptides does not improve this condition.
Login for details - Diabetes.  Some preliminary clinical research suggests that oral collagen peptides might have a small effect on glycemic indices.
Login for details - Dry skin.  It is unclear if oral collagen peptides are beneficial for dry skin; the available research is conflicting.
Login for details - Exercise-induced gastrointestinal (GI) symptoms.  It is unclear if oral collagen peptides prevent GI symptoms due to exercise.
Login for details - Exercise-induced muscle soreness.  It is unclear if oral collagen peptides prevent muscle soreness after exercise.
Login for details - Gingivitis.  It is unclear if oral collagen peptides are beneficial for patients with gingivitis.
Login for details - Hypertension.  Limited research suggests that oral collagen peptides may lower systolic or diastolic blood pressure. However, results are inconsistent.
Login for details - Joint pain.  Most research shows that oral collagen peptides might moderately reduce joint pain in young athletes. However, evidence in elderly patients is conflicting.
Login for details - Melasma. Login for details
- Obesity.  It is unclear if oral collagen peptides are beneficial for weight loss.
Login for details - Osteoarthritis.  Most research suggests that oral collagen peptides improve pain in patients with knee osteoarthritis; however, any improvement is modest and may not be considered clinically significant.
Login for details - Osteopenia.  It is unclear if oral collagen peptides prevent loss of bone mineral density (BMD) in postmenopausal adults.
Login for details - Osteoporosis.  It is unclear if oral collagen peptides improve bone mineral density (BMD).
Login for details - Pressure ulcers.  Oral collagen peptides might help to improve ulcer size and healing.
Login for details - Sarcopenia.  Oral collagen peptides might help to increase fat-free mass. However, it is unclear if collagen peptides are more beneficial than other types of protein.
Login for details - Sprains.  It is unclear if oral collagen peptides improve ankle instability after a previous sprain.
Login for details - Tendinopathy.  It is unclear if oral collagen peptides improve tendon pain.
Login for details - Wound healing.  It is unclear if oral collagen peptides improve wound healing.
Login for details - Wrinkled skin.  Some small clinical studies suggest that oral collagen peptides might help to reduce lines and wrinkles from sun damage.
Login for details
When taken by mouth: Collagen peptides are possibly safe. Collagen peptides have been safely used in doses up to 10 grams daily for up to 5 months. Side effects are rare.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if collagen peptides are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.It is not known if Collagen Peptides interacts with any medicines. Before taking Collagen Peptides, talk with your healthcare professional if you take any medications.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
Collagen peptides have most often been used by adults in doses of 2.5-10 grams daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Collagen Hydrolysate, Collagen Peptidesi, Collagène Dénaturé, Collagène Hydrolysé, Collagène Marin Hydrolysé, Denatured Collagen, Hydrolised Collagen, Hydrolysed Collagen, Hydrolyzed Collagen, Hydrolyzed Collagen Protein, Marine Collagen Hydrolysate, Protéine de Collagène Hydrolysé.
Information on this website is for informational use only and is not intended to replace professional medical advice, diagnosis, or treatment. While evidence-based, it is not guaranteed to be error-free and is not intended to meet any particular user’s needs or requirements or to cover all possible uses, safety concerns, interactions, outcomes, or adverse effects. Always check with your doctor or other medical professional before making healthcare decisions (including taking any medication) and do not delay or disregard seeking medical advice or treatment based on any information displayed on this website.
© TRC Healthcare 2023. All rights reserved. Use and/or distribution is permitted only pursuant to a valid license or other permission from TRC Healthcare.