Diosmin is a chemical called a flavonoid that is found in some plants. It's most commonly found in citrus fruits.
Diosmin might work by reducing swelling and restoring normal vein function. Diosmin also seems to have antioxidant effects. Diosmin is often taken with other plant flavonoids like hesperidin.
Diosmin is most often used for hemorrhoids and poor blood flow. It's also used for back pain and many other conditions, but there's no strong scientific evidence to support most of these uses.
- Chronic venous insufficiency (CVI).  Oral diosmin, as part of a micronized purified flavonoid fraction, seems to be beneficial for reducing symptoms of CVI. It is unclear if oral diosmin alone is beneficial.
Login for details - Hemorrhoids.  Oral diosmin, as part of a micronized purified flavonoid fraction or in combination with other compounds, seems to be beneficial for hemorrhoids.
Login for details - Venous leg ulcers.  Oral diosmin, as part of a micronized purified flavonoid fraction, seems to be beneficial for venous leg ulcers.
Login for details
- Back pain.  It is unclear if oral diosmin is beneficial for back pain.
Login for details - Chronic prostatitis and chronic pelvic pain syndrome (CP/CPPS).  It is unclear if oral diosmin, as part of a micronized purified flavonoid fraction, is beneficial for CPPS.
Login for details - Coronary artery bypass graft (CABG) surgery.  It is unclear if oral diosmin, as part of a micronized purified flavonoid fraction, is beneficial for patients undergoing CABG surgery.
Login for details - Diabetes.  It is unclear if oral diosmin, as part of a micronized purified flavonoid fraction, is beneficial for diabetes.
Login for details - Lymphedema.  It is unclear if oral diosmin, as part of a micronized purified flavonoid fraction or in combination with other compounds, is beneficial for lymphedema.
Login for details - Minor bleeding.  It is unclear if oral diosmin, as part of a micronized purified flavonoid fraction, is beneficial for minor bleeding.
Login for details - Ovarian hyperstimulation syndrome.  It is unclear if oral diosmin is beneficial for reducing the occurrence of ovarian hyperstimulation syndrome.
Login for details - Varicose veins.  It is unclear if oral diosmin, as part of a micronized purified flavonoid fraction, is beneficial for varicose veins.
Login for details - Venous thromboembolism (VTE).  It is unclear if oral diosmin is beneficial for prevention of VTE.
Login for details
When taken by mouth: Diosmin is commonly consumed from citrus fruits. Diosmin supplements are possibly safe for most people when used short-term. Diosmin can cause some side effects such as stomach pain, diarrhea, dizziness, headache, and skin redness.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Diosmin is commonly consumed from citrus fruits. Diosmin supplements are possibly safe to take with other flavonoids like hesperidin when pregnant or breast-feeding.Surgery: Diosmin might prolong bleeding and might increase the risk of bleeding during and after surgical procedures. Stop taking diosmin at least 2 weeks before a scheduled surgery.
There are no known interactions with medications. Before taking this product, talk with your health professional if you take any medications.
Herbs and supplements that might slow blood clotting: Diosmin might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.
There are no known interactions with foods.
Diosmin is commonly eaten in citrus fruits. As a supplement, it's usually taken in combination with other flavonoids, particularly hesperidin. It's most often been used by adults in doses of 450-1350 mg by mouth daily for 1-6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
3',5,7-trihydroxy-4'-methoxyflavone-7-rhamnoglucoside, Bioflavonoid, Bioflavonoid Complex, Bioflavonoid Concentrate, Bioflavonoid Extract, Bioflavonoïde, Bioflavonoïde d'Agrume, Bioflavonoïdes d'Agrumes, Citrus Bioflavones, Citrus Bioflavonoid, Citrus Bioflavonoids, Citrus Bioflavonoid Extract, Citrus Flavones, Citrus Flavonoids, Complexe de Bioflavonoïde, Concentré de Bioflavonoïde, Diosmetin, Diosmetin 7-O-rutinoside, Diosmina, Diosmine, Extrait de Bioflavonoïde, Extrait de Bioflavonoïde d'Agrume, Flavonoid, Flavonoïde, Micronised Purified Flavonoid Fraction, MPFF.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.
For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.
© Copyright 1995-2021. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.