+ Add to myCart

Inositol is a vitamin-like substance. It is found in many plants and animals. It is also produced in the human body and can be made in a laboratory. Inositol can be found in many forms (called isomers). The most common forms are myo-inositol and D-chiro-inositol.

Inositol is used to for metabolic syndrome and polycystic ovary syndrome (PCOS). It's also used for many other conditions, but there is no good scientific evidence to support most of these uses.

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
No data available.
No data available.
No data available.
No data available.

Inositol might balance certain chemicals in the body to possibly help with mental conditions such as panic disorder, depression, and obsessive-compulsive disorder. It might also help insulin work better. This might help with conditions such as polycystic ovary syndrome or diabetes during pregnancy.

When taken by mouth: Inositol is POSSIBLY SAFE for most adults when taken by mouth. It may cause nausea, stomach pain, tiredness, headache, and dizziness in some people.

When applied to the skin: There isn't enough reliable information to know if inositol is safe or what the side effects might be.

Special Precautions & Warnings:

Children: Inositol is POSSIBLY SAFE when taken by mouth for up to 12 weeks in children ages 5-12 years old. It is also POSSIBLY SAFE when used in the hospital for premature infants with a sudden and serious lung condition (acute respiratory distress syndrome or ARDS) for up to 10 days. However, inositol is POSSIBLY UNSAFE when used for longer than 10 days in premature infants with ARDS.

Pregnancy and breast-feeding: Inositol is POSSIBLY SAFEwhen taken by mouth during pregnancy. There isn't enough reliable information to know if inositol is safe to use when breast-feeding. Stay on the safe side and avoid use.

There are no known interactions with medications. Before taking this product, talk with your health professional if you take any medications.

Herbs and supplements that might lower blood sugar: Inositol might lower blood sugar. Using it with other herbs or supplements that also have this effect might lower blood sugar too much. Other herbs and supplements that might lower blood sugar include agaricus mushroom, banaba, bitter melon, cowhage, devil's claw, fenugreek, ginger, glucomannan, goat's rue, guar gum, kudzu, Panax ginseng, Siberian ginseng, willow bark and others.

There are no known interactions with foods.

The following doses have been studied in scientific research:



  • For a grouping of symptoms that increase the risk of diabetes, heart disease, and stroke (metabolic syndrome): 2 grams of a certain form of inositol (isomer myo-inositol) has been taken twice per day for one year.
  • For a hormonal disorder that causes enlarged ovaries with cysts (polycystic ovary syndrome or PCOS): 1000 to 1200 mg of a certain form of inositol (isomer D-chiro-inositol) has been used. Also, a product containing 4 grams of another form of inositol (isomer myo-inositol) plus 400 mcg of folic acid has been taken daily for up to 6 months. A combination of 550 mg of myo-inositol and 150 mg of D-chiro-inositol has also been taken twice daily for up to 12 weeks.
  • For preventing preterm birth: 2 grams of a certain form of inositol (isomer myo-inositol) plus 200 mcg of folic acid has been taken twice daily throughout pregnancy. 1100 mg of myo-inositol plus 27.6 mg of another form of inositol (isomer D-chiro-inositol) and 400 mcg of folic acid has been taken daily throughout pregnancy.

1,2,3,4,5,6-Cyclohexanehexol, 1,2,5/3,4,6-inositol, (1S)-inositol, (1S)-1,2,4/3,5,6-inositol, Antialopecia Factor, (+)-chiroinositol, cis-1,2,3,5-trans-4,6-Cyclohexanehexol, Cyclohexitol, Dambrose, D-chiro-inositol, D-Myo-Inositol, Facteur Anti-alopécique, Hexahydroxycyclohexane, Inose, Inosite, Inositol Monophosphate, Lipositol, Meso-Inositol, Méso-Inositol, Monophosphate d'Inositol, Mouse Antialopecia Factor, Myo-Inositol, Vitamin B8, Vitamine B8.

Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.

For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.

© Copyright 1995-2021. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.

trclogo Licensed from Therapeutic Research Center, LLC Copyright © 1995-2023 by Therapeutic Research Center, LLC. All Rights Reserved.