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Octacosanol is a chemical found in a variety of plants, including sugar cane and wheat germ oil. It is chemically similar to vitamin E. Octacosanol is also found in another product, called policosanol.

Octacosanol is used for athletic performance, Parkinson disease, amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), high cholesterol, and hardening of the arteries (atherosclerosis), but there is no good scientific evidence to support these uses.

Be careful not to confuse octacosanol with policosanol.

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.

Octacosanol might help improve the way the body uses oxygen.

When taken by mouth: There isn't enough reliable information to know if octacosanol is safe or what the side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if octacosanol is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

Parkinson disease: Octacosanol might make some symptoms of Parkinson disease worse if it is used with the Parkinson disease medication levodopa/carbidopa. Don't use this combination.

Levodopa/Carbidopa (Sinemet)

Interaction Rating=Moderate Be cautious with this combination.

Levodopa/carbidopa is used for Parkinson disease. Taking octacosanol along with levodopa/carbidopa might make Parkinson disease symptoms worse. Do not take octacosanol if you are taking levodopa/carbidopa.

There are no known interactions with herbs and supplements.

There are no known interactions with foods.

The appropriate dose of octacosanol depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for octacosanol. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

1-Octacosanol, Hexacosanol (26-C), N-octacosanol, Octacosyl Alcohol, Tetracosanol (24-C), Tétracosanol (24-C), Triacontanol (30-C).

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