Passion flower (Passiflora incarnata) is a climbing vine with white and purple flowers. The chemicals in passion flower have calming effects.
Passion flower is native to the southeastern United States and Central and South America. It's been traditionally used to help with sleep.
People use passion flower for anxiety, including anxiety before surgery. Some people also take passion flower for insomnia, stress, ADHD, pain, and many other conditions. But there is no good scientific evidence to support these uses. In some foods and beverages, passion flower is added for flavoring.
- Anxiety.  Oral passion flower has a long history of use as a sedative and may improve symptoms of anxiety in some patients.
Login for details - Preoperative anxiety and sedation.  Oral passion flower modestly reduces preoperative anxiety.
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- Adjustment disorders.  Oral passion flower has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Login for details - Alcohol use disorder.  Oral passion flower has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Login for details - Attention deficit-hyperactivity disorder (ADHD).  It is unclear if oral passion flower is beneficial in patients with ADHD.
Login for details - Congestive heart failure (CHF).  Oral passion flower has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Login for details - Fibromyalgia. Login for details
- Insomnia.  Small clinical studies suggest that oral passion flower may modestly improve sleep quality in patients with insomnia and poor sleep quality.
Login for details - Menopausal symptoms. Login for details
- Muscle cramps. Login for details
- Neuropathic pain. Login for details
- Opioid withdrawal.  It is unclear if oral passion flower helps to prevent opioid withdrawal.
Login for details - Seizures. Login for details
- Stress.  Oral passion flower has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
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When taken by mouth: Passion flower is likely safe for most people when used as a flavoring in foods. It's possibly safe when taken as a tea for 7 nights, or as a medicine for up to 8 weeks. It may cause side effects such as drowsiness, dizziness, and confusion.
When applied to the skin: There isn't enough reliable information to know if passion flower is safe or what the side effects might be.
Special Precautions & Warnings:
Pregnancy : Passion flower is possibly unsafe when taken by mouth during pregnancy. It might lead to early labor and other problems. There are some chemicals in the passion flower plant that might cause the uterus to contract. Don't use passion flower if you are pregnant.Breast-feeding: There isn't enough reliable information to know if passion flower is safe to use when breast-feeding. Stay on the safe side and avoid use.
Children: Passion flower is possibly safe for most children when taken by mouth for short periods of time. A specific passion flower product (Pasipay by Iran Darouk Pharmaceutical Company) has been used safely in children aged 6-13 years for up to 8 weeks.
Surgery: Passion flower might slow down the nervous system. Anesthesia and other medications used before and after surgery can also slow down the nervous system. Taking them together might slow down the nervous system too much. Talk to your healthcare provider if you are taking passion flower within 2 weeks of a scheduled surgery.
Sedative medications (CNS depressants)
Interaction Rating=Moderate Be cautious with this combination.
Passionflower might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking passionflower along with sedative medications might cause too much sleepiness.
Some sedative medications include pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), clonazepam (Klonopin), lorazepam (Ativan), zolpidem (Ambien), and others.
Herbs and supplements with sedative properties: Passion flower might cause sleepiness and slowed breathing. Taking it along with other supplements with similar effects might cause too much sleepiness and/or slowed breathing in some people. Examples of supplements with this effect include hops, kava, L-tryptophan, melatonin, and valerian.
There are no known interactions with foods.
Passion flower extract products typically provide 250-900 mg per dose. But there isn't enough reliable information to know what an appropriate dose of passion flower might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.
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