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Prickly pear cactus (Opuntia ficus-indica) is a plant native to Mexico. Its fruit and stems are commonly eaten and used as medicine in Mexican cultures.

Prickly pear cactus might lower blood sugar and cholesterol levels by reducing how much the stomach absorbs.

People most commonly use prickly pear cactus for diabetes. It is also used for enlarged prostate, hangover, high cholesterol, and many other purposes, but there is no good scientific evidence to support these uses.

NatMed Pro rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
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  • Diabetes.  Oral prickly pear cactus might help reduce postprandial blood glucose in patients with diabetes.
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When taken by mouth: Prickly pear cactus is likely safe when the fruit and cactus pads are eaten as food. The pads and fruit are possibly safe when taken as medicine for a short period of time. Prickly pear cactus can cause minor side effects in some people, including diarrhea, nausea, bloating, and heartburn.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if prickly pear cactus is safe to use when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.

Surgery: Prickly pear cactus might affect blood sugar levels, making blood sugar control difficult during and after surgery. Stop using prickly pear cactus at least 2 weeks before a scheduled surgery.

Medications for diabetes (Antidiabetes drugs)

Interaction Rating=Moderate Be cautious with this combination.

Prickly pear cactus might lower blood sugar levels. Taking prickly pear cactus along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.

Herbs and supplements that might lower blood sugar: Prickly pear cactus might lower blood sugar. Taking it with other supplements with similar effects might lower blood sugar too much. Examples of supplements with this effect include aloe, bitter melon, cassia cinnamon, and chromium.

There are no known interactions with foods.

There isn't enough reliable information to know what an appropriate dose of prickly pear cactus might be. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult a healthcare professional before using.

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