Available on Wellkasa
Probiotics are live bacteria and yeasts that are thought to improve health. The most common probiotics include lactobacillus, bifidobacteria, and Saccharomyces boulardii.
Many bacteria and other organisms live in our bodies normally. These "good" bacteria and yeasts can help break down food, absorb nutrients, and fight off "bad" organisms that might cause diseases. Probiotics are sometimes taken as supplements and are also found in foods such as yogurt.
Probiotics are used for many different types of diarrhea, irritable bowel syndrome (IBS), constipation, and many other conditions. Keep in mind that not all probiotics have the same effects. So, one probiotic or combination of probiotics may be helpful for certain conditions, while other probiotics are not. Also, there is no good evidence to support using any probiotics for COVID-19.
- Abdominal pain.  Oral probiotics containing L. reuteri seem to reduce abdominal pain in children 4 years and up. It is unclear if other probiotics are beneficial for abdominal pain.
Login for details - Antibiotic-associated diarrhea.  Oral probiotics, especially lactobacillus and Saccharomyces boulardii, seem to reduce the risk of antibiotic-associated diarrhea (AAD) in adults and children.
Login for details - Atopic dermatitis (eczema).  Oral probiotics, especially lactobacillus, seem to be beneficial for atopic dermatitis prevention in children. However, oral probiotics do not seem to be beneficial for atopic dermatitis treatment.
Login for details - Atopic disease.  Oral L. rhamnosus GG seems to be beneficial for the prevention of atopic disease in children. However, it is unclear if other probiotics are beneficial.
Login for details - Bacterial vaginosis.  Oral probiotics, alone or with antibiotics, seem to be beneficial for bacterial vaginosis.
Login for details - Clostridium difficile infection.  Taking oral probiotics with antibiotics might reduce the risk of an initial C. difficile infection in certain high-risk patients. Also, in some patients, oral Saccharomyces boulardii might reduce the risk of C. difficile infection RECURRENCE. It is unclear if other probiotics are beneficial for the prevention of recurrence.
Login for details - Colic.  Oral L. reuteri DSM 17938 seems to be beneficial for colic treatment. However, oral probiotics don't seem to be beneficial for colic prevention.
Login for details - Constipation.  Oral probiotics seem to be beneficial for constipation in adults, but not in children.
Login for details - Diarrhea.  Oral probiotics seem to be beneficial for diarrhea in adults and children.
Login for details - Fetal and premature infant mortality.  Oral probiotics, especially combination treatments, seem to be beneficial for the prevention of mortality in premature infants.
Login for details - Helicobacter pylori.  Oral probiotics, in conjunction with most standard H. pylori eradication therapies, seems to be beneficial for improving eradication rates.
Login for details - Hepatic encephalopathy.  Oral probiotics seem to be beneficial for hepatic encephalopathy.
Login for details - Hypercholesterolemia.  Oral probiotics containing lactobacillus seem to be beneficial for hypercholesterolemia.
Login for details - Irritable bowel syndrome (IBS).  Oral probiotics are conditionally recommended by the American College of Gastroenterology for the relief of global IBS symptoms, such as abdominal pain.
Login for details - Necrotizing enterocolitis (NEC).  Oral probiotics, especially multi-strain products, seem to be beneficial for NEC prevention in low birth weight infants. The American Gastroenterological Association conditionally recommends probiotics, especially lactobacillus and bifidobacteria, for the prevention of NEC.
Login for details - Oral mucositis.  Oral probiotics containing L. brevis CD2 in the form of lozenges seem to be beneficial for preventing oral mucositis caused by radiation or chemotherapy.
Login for details - Otitis media.  Oral probiotics seem to be beneficial for the prevention of otitis media in children.
Login for details - Pouchitis.  Oral probiotics containing lactobacillus and bifidobacteria seem to be beneficial for pouchitis.
Login for details - Respiratory tract infections.  Oral probiotics seem to be beneficial for respiratory tract infection prevention.
Login for details - Rheumatoid arthritis (RA).  Oral probiotics containing lactobacillus alone seem to be beneficial for RA.
Login for details - Rotaviral diarrhea.  Oral probiotics containing Saccharomyces boulardii seem to be beneficial for the treatment of rotaviral diarrhea in children. It is unclear if other probiotics are beneficial.
Login for details - Traveler's diarrhea.  Oral probiotics, especially Saccharomyces boulardii, seem to be beneficial for the prevention of traveler's diarrhea.
Login for details
- Age-related cognitive decline.  Oral probiotics containing bifidobacteria don't seem to be beneficial for age-related cognitive decline. It is unclear if other probiotics may be beneficial.
Login for details - Anxiety.  Oral probiotics don't seem to be beneficial for anxiety.
Login for details - Crohn disease.  Oral probiotics don't seem to be beneficial for inducing or maintaining remission of this condition.
Login for details - Exercise-induced respiratory infections.  Oral probiotics, especially lactobacillus, don't seem to be beneficial for preventing respiratory infections related to exercise.
Login for details - Obesity.  Oral probiotics don't seem to be beneficial for weight loss.
Login for details - Sepsis.  Oral probiotics don't seem to be beneficial for preventing sepsis in preterm infants.
Login for details - Vaginal candidiasis.  Oral or intravaginal probiotics don't seem to be beneficial for vaginal candidiasis.
Login for details
- Acne.  Small clinical studies suggest that oral probiotics are beneficial for acne.
Login for details - Allergic rhinitis (hay fever).  It is unclear if oral probiotics are beneficial for allergic rhinitis.
Login for details - Critical illness (trauma).  It is unclear if oral probiotics are beneficial for critically ill patients.
Login for details - Dental caries.  It is unclear if oral probiotics are beneficial for the prevention of dental caries.
Login for details - Diabetes.  It is unclear if oral probiotics are beneficial for the treatment of type 2 diabetes or gestational diabetes. Oral probiotics are unlikely to be beneficial for gestational diabetes prevention and may be harmful during pregnancy.
Login for details - Nonalcoholic fatty liver disease (NAFLD).  It is unclear if oral probiotics are beneficial for NAFLD.
Login for details - Small intestinal bacterial overgrowth (SIBO).  It is unclear if oral probiotics are beneficial for SIBO treatment or prevention.
Login for details - Ulcerative colitis.  It is unclear if oral probiotics are beneficial for inducing remission or maintaining remission in patients with ulcerative colitis.
Login for details - Urinary tract infections (UTIs).  It is unclear if oral or vaginal probiotics are beneficial for UTI prevention or recurrence.
Login for details - Ventilator-associated pneumonia (VAP).  It is unclear if oral probiotics are beneficial for the prevention of VAP in critically ill patients.
Login for details
When taken by mouth: Probiotics are likely safe for most adults. Lactobacillus probiotics appear to be safe when taken for up to 9 months. Bifidobacteria probiotics appear to be safe when taken for up to 12 months. Streptococcus thermophilus probiotics appear to be safe when taken for up to 12 months. Saccharomyces boulardii probiotics appear to be safe when taken for up to 15 months. Side effects are usually mild and most often include gas or bloating. There isn't enough reliable information about the safety of other probiotic species.
When inserted into the vagina: Probiotics containing lactobacillus are likely safe when used short-term. There isn't enough reliable information to know if other probiotic species are safe.
Special Precautions & Warnings:
Pregnancy and breast-feeding: Probiotics containing certain lactobacillus or bifidobacteria species are possibly safe when used by mouth when pregnant or breast-feeding. There isn't enough reliable information to know if other probiotic species are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: Probiotic products containing bifidobacteria or lactobacillus are likely safe in children. Bifidobacteria probiotics appear to be safe in children when used for up to 12 months. Lactobacillus probiotics appear to be safe in children when used for up to 12 weeks. Probiotics containing Saccharomyces boulardii are possibly safe when used in children. There isn't enough reliable information to know if other probiotic species are safe for children.
Central lines: Infections of the blood have been reported in people who have central lines and take probiotics containing either lactobacillus or Saccharomyces boulardii. In many cases, infections were caused when the catheter became contaminated by the air or surfaces or hands that had touched the probiotics. If you have a central line, talk with your healthcare provider before taking probiotics.
Digestive system problems: Infections of the blood have been reported in a small number of people with digestive system conditions such as short bowel syndrome, ulcerative colitis, or intestinal obstruction (after abdominal surgery) who were taking probiotics containing lactobacillus or bifidobacterium probiotics. If you have any of these conditions, talk with your healthcare provider before taking probiotics.
Weakened immune system: Probiotics have caused blood infections in a small number of people with weakened immune systems. This includes people with HIV/AIDS or cancer, or people who are taking medications to prevent transplant rejection. The actual number of cases of probiotic-related infections is hard to determine. If you have a weakened immune system, talk with your healthcare provider before taking probiotics.
Damaged heart valves: Probiotic preparations containing lactobacillus can cause an infection in the inner lining of the heart chambers and heart valve. This is extremely rare, but people with damaged heart valves might be more likely to develop this type of infection. People with damaged heart valves should stop taking probiotics before dental procedures or surgical procedures.
Yeast allergy: People with yeast allergy can be allergic to probiotic products containing Saccharomyces boulardii and should avoid these products if possible.
There are no known interactions with medications. Before taking this product, talk with your health professional if you take any medications.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
Probiotics are commonly taken in dietary supplements and foods, such as yogurt. The most common probiotics found in these products include lactobacillus, bifidobacteria, and Saccharomyces boulardii. But many other bacteria and yeast species can be found in probiotic products.
The strength of bacterial probiotics is usually given as the number of living organisms, or colony-forming units (CFU), per capsule. The strength of fungal probiotics is usually given in micrograms or milligrams. To learn more about how specific probiotics are typically used, review our monographs on those topics.
Probiotic, Probiotique.
Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.
For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.
© Copyright 1995-2021. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.