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Saccharomyces boulardii is a yeast believed to be a strain of Saccharomyces cerevisiae. It is likely effective for treating certain types of diarrhea.
Saccharomyces boulardii is called a "probiotic," a friendly organism that helps to fight off "bad" organisms that might cause diseases. Saccharomyces boulardii is different from other strains of Saccharomyces cerevisiae, commonly known as brewer's yeast and baker's yeast.
Saccharomyces boulardii is most commonly used for treating and preventing diarrhea, including rotaviral diarrhea in children. It has some evidence of use for other types of diarrhea, acne, and a digestive tract infection that can lead to ulcers. There is no good evidence to support using Saccharomyces boulardii for COVID-19.
- Diarrhea. In children, oral Saccharomyces boulardii reduces the duration of acute diarrhea and the duration of hospitalization for acute diarrhea. It is unclear if it is beneficial in adults.
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- Antibiotic-associated diarrhea. Oral Saccharomyces boulardii seems to be beneficial for the prevention of antibiotic-associated diarrhea (AAD) in most patients.
Login for details - Clostridium difficile infection. Oral Saccharomyces boulardii seems to be beneficial for preventing C. difficile infection. In combination with vancomycin or metronidazole, oral Saccharomyces boulardii seems to be beneficial for preventing recurrence of C. difficile infection.
Login for details - Helicobacter pylori. Oral Saccharomyces boulardii seems to be beneficial for reducing adverse effects associated with standard therapy for H. pylori eradication.
Login for details - Necrotizing enterocolitis (NEC). Login for details
- Rotaviral diarrhea. In children, oral Saccharomyces boulardii seems to reduce the duration of rotaviral diarrhea.
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- Sepsis. In preterm infants, oral Saccharomyces boulardii does not seem to be beneficial for sepsis prevention.
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- Acne. It is unclear if oral Saccharomyces boulardii is beneficial for acne.
Login for details - Cholera. It is unclear if oral Saccharomyces boulardii is beneficial for cholera.
Login for details - Cognitive function. It is unclear if oral Saccharomyces boulardii is beneficial for cognitive function.
Login for details - Crohn disease. It is unclear if oral Saccharomyces boulardii is beneficial for this condition.
Login for details - Critical illness (trauma). It is unclear if oral Saccharomyces boulardii is beneficial for reducing diarrhea in critically ill patients.
Login for details - Cystic fibrosis. It is unclear if oral Saccharomyces boulardii is beneficial for cystic fibrosis.
Login for details - Exercise-induced muscle soreness. Oral Saccharomyces boulardii has only been evaluated in combination with other ingredients; its effect when used alone is unclear.
Login for details - Heart failure. It is unclear if oral Saccharomyces boulardii is beneficial for heart failure.
Login for details - HIV/AIDS-related diarrhea. It is unclear if oral Saccharomyces boulardii is beneficial for this condition.
Login for details - Hypercholesterolemia. It is unclear if oral Saccharomyces boulardii is beneficial for hypercholesterolemia.
Login for details - Intestinal parasite infection. It is unclear if oral Saccharomyces boulardii is beneficial for intestinal parasite infection.
Login for details - Irritable bowel syndrome (IBS). It is unclear if oral Saccharomyces boulardii is beneficial for IBS.
Login for details - Low birth weight. It is unclear if oral Saccharomyces boulardii is beneficial for growth in low birth weight infants.
Login for details - Neonatal jaundice. It is unclear if oral Saccharomyces boulardii is beneficial for neonatal jaundice prevention or treatment.
Login for details - Small intestinal bacterial overgrowth (SIBO). It is unclear if oral Saccharomyces boulardii is beneficial for SIBO.
Login for details - Travelers' diarrhea. It is unclear if oral Saccharomyces boulardii is beneficial for traveler's diarrhea.
Login for details - Ulcerative colitis. It is unclear if oral Saccharomyces boulardii is beneficial for ulcerative colitis.
Login for details - Urinary tract infections (UTIs). Login for details
- Vaginal candidiasis. Login for details
When taken by mouth: Saccharomyces boulardii is likely safe for most adults when used for up to 15 months. It can cause gas in some people.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if Saccharomyces boulardii is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: Saccharomyces boulardii is possibly safe for children when taken by mouth appropriately. However, diarrhea in children should be evaluated by a healthcare professional before using Saccharomyces boulardii.
Elderly: The elderly might have an increased risk of fungal infection when taking Saccharomyces boulardii. Stay on the safe side and avoid use.
Weakened immune system: Saccharomyces boulardii has caused fungal infections in people with weakened immune systems. This includes people with HIV/AIDS or cancer, or people who are taking medications to prevent rejection of a transplanted organ. In many cases, fungemia resulted from catheter contamination by air, environmental surfaces, or hands that have been contaminated with Saccharomyces boulardii. If you have a weakened immune system, talk with your healthcare provider before taking Saccharomyces boulardii.
Yeast allergy: People with yeast allergy can be allergic to products containing Saccharomyces boulardii. Stay on the safe side and avoid these products.
Medications for fungal infections (Antifungals)
Interaction Rating=Minor Be watchful with this combination.
Saccharomyces boulardii is a fungus. Medications for fungal infections help reduce fungus in and on the body. Taking Saccharomyces boulardii with medications for fungal infections can reduce the effectiveness of Saccaromyces boulardii.
Some medications for fungal infection include fluconazole (Diflucan), terbinafine (Lamisil), itraconazole (Sporanox), and others.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
In adults, Saccharomyces boulardii has most often been taken by mouth in doses of 500-1000 mg (about 10-20 billion colony-forming units) daily for 4 weeks. In children, Saccharomyces boulardii has most often been taken by mouth in doses of 250-500 mg (about 5-10 billion colony-forming units) for up to 4 weeks.
Probiotic, Probiotique, Saccharomyces, Saccharomyces Boulardii CNCM I-745, Saccharomyces Boulardii HANSEN CBS 5926, Saccharomyces Boulardii Lyo CNCM I-745, Saccharomyces Boulardius, Saccharomyces Cerevisiae Boulardii, Saccharomyces Cerevisiae (Boulardii), Saccharomyces Cerevisiae (Boulardii) HANSEN CBS 5926, Saccharomyces Cerevisiae HANSEN CBS 5926, Saccharomyces cerevisiae var boulardii, S. Boulardii, SCB.
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