+ Add to myCart

Thunder god vine (Tripterygium wilfordii) is a vine that grows in southeast China. Its extracts are used in traditional and pharmaceutical Chinese medicine.

Thunder god vine contains chemicals that might relieve swelling and change the way the immune system works. This might help with arthritis and other conditions. Also, thunder god vine contains chemicals that might alter sperm and decrease male fertility.

People use thunder god vine for rheumatoid arthritis (RA), Crohn disease, kidney problems, mouth sores, and eye problems in people with an overactive thyroid. It is also used for eczema, birth control, menstrual cramps, and many other conditions, but there is no good scientific evidence to support many of these uses.

Natural Medicines rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, Ineffective, and Insufficient Evidence to Rate.
No data available.
No data available.
No data available.
No data available.
Info
No data available.

When taken by mouth: Thunder god vine is possibly safe for most people. It's usually well tolerated. Side effects might include stomach upset, missed menstrual periods, skin reactions, nausea, diarrhea, and headache.

When applied to the skin: Thunder god vine is possibly safe.

Special Precautions & Warnings:

Pregnancy: Thunder god vine is likely unsafe when taken by mouth during pregnancy. It might cause birth defects.

Breast-feeding: There isn't enough reliable information to know if thunder god vine is safe to use when breast-feeding. Stay on the safe side and avoid use.

Weakened immune system: Large doses of thunder god vine might weaken the immune system. If you already have a weakened immune system due to a medical condition, or from taking certain medications, avoid using thunder god vine. It might decrease your body's ability to fight off infection.

Weakened bones (osteoporosis): Thunder god vine can reduce bone strength. If you have osteoporosis or are at risk for osteoporosis, don't use thunder god vine.

Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)

Interaction Rating=Moderate Be cautious with this combination.

Some medications are changed and broken down by the liver. Thunder god vine might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)

Interaction Rating=Moderate Be cautious with this combination.

Some medications are changed and broken down by the liver. Thunder god vine might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.

Medications that decrease break down of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inhibitors)

Interaction Rating=Moderate Be cautious with this combination.

Thunder god vine is changed and broken down by the liver. Some drugs decrease how quickly the liver changes and breaks down thunder god vine. This could change the effects and side effects of thunder god vine.

Medications that decrease the immune system (Immunosuppressants)

Interaction Rating=Moderate Be cautious with this combination.

Large doses of thunder god vine can decrease the activity of the immune system. Some medications, such as those used after a transplant, also decrease the activity of the immune system. Taking thunder god vine along with these medications might cause the activity of the immune system to drop too low.

There are no known interactions with herbs and supplements.

There are no known interactions with foods.

Thunder god vine extract has most often been used by adults in doses of 30-120 mg by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Huang-T'eng Ken, Lei Gong Teng, Lei-Kung T'eng, Seven Step Vine, Taso-Ho-Hua, Threewingnut, Tonnerre de la Vigne de Dieu, Tripterigium Wilfordii, Tripterygium wilfordii, Vigne du Tonnerre Divin, Yellow Vine.

Natural Medicines disclaims any responsibility related to medical consequences of using any medical product. Effort is made to ensure that the information contained in this monograph is accurate at the time it was published. Consumers and medical professionals who consult this monograph are cautioned that any medical or product related decision is the sole responsibility of the consumer and/or the health care professional. A legal License Agreement sets limitations on downloading, storing, or printing content from this Database. Except for any possible exceptions written into your License Agreement, no reproduction of this monograph or any content from this Database is permitted without written permission from the publisher. Unlawful to download, store, or distribute content from this site.

For the latest comprehensive data on this and every other natural medicine, health professionals should consult the Professional Version of the Natural Medicines. It is fully referenced and updated daily.

© Copyright 1995-2022. Therapeutic Research Faculty, publishers of Natural Medicines, Prescriber's Letter, and Pharmacist's Letter. All rights reserved.

trclogo Licensed from Therapeutic Research Center, LLC Copyright © 1995-2023 by Therapeutic Research Center, LLC. All Rights Reserved.