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Vitamin E is an essential nutrient that includes both tocotrienols and tocopherols. Tocotrienols have double bonds and are found in palm and rice bran oil.
Tocotrienols exist in four different forms: alpha-, beta-, gamma-, and delta-tocotrienols. Tocotrienols seem to have many different effects in the body. They might lower cholesterol levels and provide heart health benefits.
People use tocotrienols for high cholesterol, cancer, stroke, aging, and many other conditions, but there is no good scientific evidence to support these uses.
To learn about tocopherols, another source of vitamin E, review vitamin E.
- Hypercholesterolemia. Oral tocotrienols are not likely to induce clinically meaningful improvements in cholesterol levels.
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- Age-related cognitive decline. Oral tocotrienols have only been evaluated in combination with other ingredients; their effect when used alone is unclear.
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- Alzheimer disease. Login for details
- Alopecia areata. Login for details
- Breast cancer. It is unclear if oral tocotrienols are beneficial for improving early breast cancer outcomes or preventing recurrence.
Login for details - Chronic kidney disease (CKD). Login for details
- Diabetes. It is unclear if oral tocotrienols are beneficial in patients with diabetes.
Login for details - Diabetic nephropathy. It is unclear if oral tocotrienol-rich vitamin E is beneficial for slowing diabetic nephropathy progression.
Login for details - Familial dysautonomia. It is unclear if oral tocotrienols are beneficial for familial dysautonomia outcomes.
Login for details - Hypertrophic scars. It is unclear if topical tocotrienols improve hypertrophic scar appearance or vascularity.
Login for details - Impaired glucose tolerance (prediabetes). It is unclear whether oral tocotrienols are beneficial in patients with prediabetes.
Login for details - Nonalcoholic fatty liver disease (NAFLD). Small clinical studies suggest that oral tocotrienols may modestly improve steatosis and other outcomes in patients with NAFLD.
Login for details - Postmenopausal conditions. It is unclear if oral tocotrienols are beneficial for improving symptoms in postmenopausal patients.
Login for details - Stroke. It is unclear if oral tocotrienols are beneficial for improving outcomes in patients after stroke or transient ischemic attack (TIA).
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When taken by mouth: Tocotrienols are possibly safe when used at a dose of 200 mg daily for up to 5 years. They're usually well tolerated.
When applied to the skin: There isn't enough reliable information to know if tocotrienols are safe. Tocotrienol cream can cause mild itching in some people.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if tocotrienols are safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Minor Be watchful with this combination.
Tocotrienols might slow blood clotting. Taking tocotrienols along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
There are no known interactions with herbs and supplements.
There are no known interactions with foods.
Tocotrienols have most often been used by adults in doses of 200-600 mg by mouth daily for up to 6 months. Speak with a healthcare provider to find out what dose might be best for a specific condition.
Alpha-Tocotrienol, Alpha-Tocotriénol, Alpha Tocotrienol, Beta-Tocotrienol, Bêta-Tocotriénol, Beta Tocotrienol, Concentré de Tocotriénol, D-Alpha Tocotrienol, D-Alpha Tocotriénol, D-Gamma Tocotrienol, D-Gamma-Tocotriénol, Delta-Tocotrienol, Delta-Tocotriénol, Delta Tocotrienol, Epsilon-Tocopherol, Epsilon-Tokoferol, Epsilon Tocopherol, Gamma-Tocotrienol, Gamma-Tocotriénol, Gamma Tocotrienol, Mixed Tocotrienols, Palm Tocotrienols, Rice Tocotrienols, Tocotrienol, Tocotriénol, Tocotrienol Concentrate, Tocotriénols, Tocotriénols de Palme, Tocotriénols de Riz, Tocotriénols Mixtes, Zeta1-Tocopherol.
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