Umckaloabo (Pelargonium sidoides) is a flowering plant native to South Africa. It's used as medicine by the native populations of South Africa.
Umckaloabo might work by killing bacteria or preventing bacteria from attaching to surfaces within the body.
People use umckaloabo for bronchitis, common cold, COPD, sore throat, asthma, and many other conditions, but there is no good scientific evidence to support most of these uses.
Umckaloabo is sometimes called geranium. Don't confuse umckaloabo with rose geranium oil or spotted geranium. These are not the same.
- Acute Bronchitis.  Oral umckaloabo extract (EPs 7630, Dr. Willmar Schwabe Pharmaceuticals) may be beneficial in adults and children with acute bronchitis when initiated within 48 hours of symptom onset.
Login for details - Chronic obstructive pulmonary disease (COPD).  Oral umckaloabo extract (EPs 7630, Dr. Willmar Schwabe Pharmaceuticals) may decrease the frequency of exacerbations, improve symptoms, and reduce the need for antibiotics in patients with COPD; however, it does not seem to reduce the overall risk of exacerbations.
Login for details - Common cold.  Oral umckaloabo extract (EPs 7630, Dr. Willmar Schwabe Pharmaceuticals) may reduce the severity and duration of cold symptoms and improve sleep quality in adults with the common cold.
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- Asthma.  It is unclear if oral umckaloabo extract is beneficial in children with asthma who have an active viral upper respiratory tract infection.
Login for details - Genital herpes. Login for details
- Herpes labialis (cold sores). Login for details
- Rhinosinusitis.  Small clinical studies suggest that oral umckaloabo root extract may improve symptoms in adults with rhinosinusitis.
Login for details - Tonsillopharyngitis.  It is unclear if oral umckaloabo extract is beneficial in children with tonsillopharyngitis.
Login for details - Upper respiratory tract infection (URTI).  A small clinical study suggests that oral umckaloabo root extract may improve symptoms in children with URTIs.
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When taken by mouth: A specific umckaloabo extract (EPs 7630, Dr. Willmar Schwabe Pharmaceuticals) is likely safe when used for up to 24 weeks. There isn't enough reliable information to know if it is safe when taken for longer periods of time. Side effects might include stomach upset. Allergic reactions are also possible.
Special Precautions & Warnings:
Pregnancy and breast-feeding: There isn't enough reliable information to know if umckaloabo is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.Children: A specific umckaloabo extract (EPs 7630, Dr. Willmar Schwabe Pharmaceuticals) is possibly safe when taken by mouth for up to one week. There isn't enough reliable information to know if it is safe when taken for longer periods of time.
Diseases of the immune system such as multiple sclerosis (MS), lupus (systemic lupus erythematosus, SLE), rheumatoid arthritis (RA), or other conditions: Umckaloabo might cause the immune system to become more active. This could increase the symptoms of these diseases. If you have one of these conditions, it's best to avoid using umckaloabo.
Surgery: Umckaloabo might slow blood clotting. It might increase the risk for bleeding during surgical procedures. Stop using umckaloabo at least 2 weeks before a scheduled surgery.
Medications that decrease the immune system (Immunosuppressants)
Interaction Rating=Moderate Be cautious with this combination.
Umckaloabo can increase the activity of the immune system. Some medications, such as those used after a transplant, decrease the activity of the immune system. Taking umckaloabo along with these medications might decrease the effects of these medications.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating=Moderate Be cautious with this combination.
Umckaloabo might slow blood clotting. Taking umckaloabo along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
Herbs and supplements that might slow blood clotting: Umckaloabo might slow blood clotting and increase the risk of bleeding. Taking it with other supplements with similar effects might increase the risk of bleeding in some people. Examples of supplements with this effect include garlic, ginger, ginkgo, nattokinase, and Panax ginseng.
There are no known interactions with foods.
A specific umckaloabo root extract (EPs 7630, Dr. Willmar Schwabe Pharmaceutical) has most often been used by adults as 30-60 drops of solution (1.5-3 mL) taken by mouth three times daily for 7-10 days. It's also available in tablets. In children, dosing depends on age. Speak with a healthcare provider to find out what dose might be best for a specific condition.
African Geranium, EPs 7630, Geranien, Geranio Sudafricano, Geranium, Géranium d'Afrique, Géranium d'Afrique du Sud, Géranium du Cap, Geranium Root, Ikhubalo, Icwayiba, i-Yeza lezikali, Kalwerbossie, Khoaara e Nyenyane, Pelargonien, Pelargonio Sudafricano, Pelargonium Root, Pélargonium d'Afrique, Pélargonium du Cap, Pelargonium sidoides, Rabas, Rabassam, Racine de Géranium, Racine de Pélargonium, South African Geranium, Uvendle.
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